The Application of Mesenchymal Stem Cells on Wound Repair and Regeneration

In the past decades, regenerative medicine applied on skin lesions has been a field of constant improvement for both human and veterinary medicine. The process healing cutaneous wound injuries implicates well-organized cascade molecular biological processes. However, sometimes normal fails can result in chronic lesion. addition, wounds are considered an increasing clinical impairment, due to progressive ageing population, as well prevalence concomitant diseases, such diabetes obesity, that represent risk-aggravating factors development lesions. Stem cells’ potential recognized worldwide, including towards lesion repair, Tissue engineering techniques have long successfully associated with stem cell therapies, namely application three-dimensional (3D) bioprinted scaffolds. With this review, we intend explore several sources promising aptitude regeneration, different used deliver those cells provide supporting extracellular matrix environment, effective outcomes. Furthermore, studies discussed, vitro vivo, terms their relevance regeneration field.